I'll add one more thing, and that satirising Islam IS punching up. The 'up' is the direction of undue privilege, and there is no greater undue privilege than a belief that your personal thoughts and ideas should be coddled or they have a right to kill you and people around you.
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Those gunmen didn't stand a chance, punching up against people armed with pencils.
Drawing an image of Muhammad is not satire, no more than Catholic images of Jesus are satire.